From the Washington, D.C. area:

Take Constitution Ave NW / US 50
Merge onto I-66 W / US-50 W.
Take the US-50 W / Arlington Blvd / GW Parkway exit.
Merge onto George Washington Memorial Pkwy N / GW Pkwy N.
Merge onto I-495 N / Capital Beltway toward Maryland
Merge onto I-270 SPUR N on the LEFT toward Rockville / Frederick.
Merge onto I-270N via EXIT 8 (Shady Grove Rd)
Keep to the Left on the exit ramp
Turn Left onto Shady Grove Rd.
Turn Right onto Key West Blvd
Turn Left onto Medical Center Dr.

From the Frederick, Maryland area:

US-40 E toward I-270 S / I-70
US-40 E becomes I-270
Travel I-270 S for appoximately 23.5 miles
Take Exit 8 Shady Grove Rd
Keep to the Right on the exit ramp
Turn Right onto Shady Grove Rd.
Turn Right onto Key West Blvd
Turn Left onto Medical Center Dr.

From the Fairfax County, Virginia area:

Lee Jackson Memorial Hwy / US-50 W
Merge onto I-66 E toward Washington
Take the US-50 W / Arlington Blvd / GW Parkway exit
Merge onto George Washington Memorial Pkwy N / GW Pkwy N
Merge onto I-495 N / Capital Beltway toward Maryland
Merge onto I-270 SPUR N on the LEFT toward Rockville / Frederick.
Merge onto I-270N via EXIT 8 (Shady Grove Rd)
Keep to the Left on the exit ramp
Turn Left onto Shady Grove Rd.
Turn Right onto Key West Blvd
Turn Left onto Medical Center Dr.